TRAPS: Rivaroxaban versus warfarin for secondary prevention in antiphospholipid syndrome [Classics Series]

This study summary is an excerpt from 2 Minute Medicine’s book The Classics in Medicine: Summaries of the Landmark Trials 1. This study was discontinued prematurely due to excess thromboembolic and haemorrhage in patients treated with rivaroxaban compared to warfarin. 2. There were no deaths from thromboembolic or haemorrhage in either group. Original publication date: … Read more

RE-VERSE AD Study: Idarucizumab for the Reversal of Anticoagulation by Dabigatran [Classics Series]

This study summary is an excerpt from 2 Minute Medicine’s book The Classics in Medicine: Summaries of the Landmark Trials 1. This study established that idarucizumab is effective in reversing anticoagulation by the direct thrombin inhibitor Dabigatran. 2. Idarucizumab started working within minutes, supporting use in emergency situations. Original Publication Date: June 2015 Study overview: … Read more